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1

Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria

Rhian E. Hayward, Joseph L. DeRisi, Suad Alfadhli, David C. Kaslow, Patrick O. Brown, Pradipsinh K. Rathod

Journal:

Molecular Microbiology

Année:

2000

Langue:

english

Fichier:

PDF, 311 KB

english, 2000

2

A coupled radiometric assay for dihydrofolate reductase based on the oxidative decarboxylation of d-6-phospho-[1-14C]gluconate

Pradipsinh K. Rathod, Philip Reyes

Journal:

Analytical Biochemistry

Année:

1983

Langue:

english

Fichier:

PDF, 447 KB

english, 1983

3

Microfluidic approaches to malaria pathogenesis

Meher Antia, Thurston Herricks, Pradipsinh K. Rathod

Journal:

Cellular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 246 KB

english, 2008

4

Deformability limits of Plasmodium falciparum-infected red blood cells

Thurston Herricks, Meher Antia, Pradipsinh K. Rathod

Journal:

Cellular Microbiology

Année:

2009

Langue:

english

Fichier:

PDF, 821 KB

english, 2009

5

Prized malaria drug target nailed

Rathod, Pradipsinh K., Phillips, Margaret A.

Journal:

Natural Structural Biology

Année:

2003

Langue:

english

Fichier:

PDF, 686 KB

english, 2003

6

Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitors with Potent and Selective Activity against the Malaria Parasite Plasmodium falciparum

Phillips, Margaret A., Gujjar, Ramesh, Malmquist, Nicholas A., White, John, El Mazouni, Farah, Baldwin, Jeffrey, Rathod, Pradipsinh K.

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 531 KB

english, 2008

7

Plasmodium falciparum:Direct Cloning and Expression of Pyrimethamine-Sensitive and Pyrimethamine-Resistant Dihydrofolate Reductase Domains

Mohammad Hekmat-Nejad, Pei-Chieh Lee, Pradipsinh K. Rathod

Journal:

Experimental Parasitology

Année:

1997

Langue:

english

Fichier:

PDF, 104 KB

english, 1997

8

Plasmodium falciparum:Kinetic Interactions of WR99210 with Pyrimethamine-Sensitive and Pyrimethamine-Resistant Dihydrofolate Reductase

Mohammad Hekmat-Nejad, Pradipsinh K. Rathod

Journal:

Experimental Parasitology

Année:

1997

Langue:

english

Fichier:

PDF, 188 KB

english, 1997

9

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

Philip Reyes, Pradipsinh K. Rathod, Donald J. Sanchez, John E.K. Mrema, Karl H. Rieckmann, Hans-G. Heidrich

Journal:

Molecular and Biochemical Parasitology

Année:

1982

Langue:

english

Fichier:

PDF, 953 KB

english, 1982

10

Identification of a Plasmodium falciparum histone 2A gene

Kathleen A. Creedon, David C. Kaslow, Pradipsinh K. Rathod, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Année:

1992

Langue:

english

Fichier:

PDF, 192 KB

english, 1992

11

Differential drug binding by the highly conserved Plasmodium falciparum thymidylate synthase

Cullen K.T. Pang, Surya Kanta De, John White, Frederick S. Buckner, Gabriele Varani, Pradipsinh K. Rathod

Journal:

Molecular and Biochemical Parasitology

Année:

2005

Langue:

english

Fichier:

PDF, 155 KB

english, 2005

12

Cell-free production of functional Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

Devaraja G. Mudeppa, Cullen K.T. Pang, Takafumi Tsuboi, Yaeta Endo, Fredrick S. Buckner, Gabriele Varani, Pradipsinh K. Rathod

Journal:

Molecular and Biochemical Parasitology

Année:

2007

Langue:

english

Fichier:

PDF, 387 KB

english, 2007

13

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

Richard T. Eastman, John White, Oliver Hucke, Kohei Yokoyama, Christophe L.M.J. Verlinde, Michael A. Hast, Lorena S. Beese, Michael H. Gelb, Pradipsinh K. Rathod, Wesley C. Van Voorhis

Journal:

Molecular and Biochemical Parasitology

Année:

2007

Langue:

english

Fichier:

PDF, 313 KB

english, 2007

14

Catalytic and ligand-binding characteristics of Plasmodium falciparum serine hydroxymethyltransferase

Cullen K.T. Pang, Joshua H. Hunter, Ramesh Gujjar, Ramulu Podutoori, Julie Bowman, Devaraja G. Mudeppa, Pradipsinh K. Rathod

Journal:

Molecular and Biochemical Parasitology

Année:

2009

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2009

15

Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection

Suresh M. Ganesan, Joanne M. Morrisey, Hangjun Ke, Heather J. Painter, Kamal Laroiya, Margaret A. Phillips, Pradipsinh K. Rathod, Michael W. Mather, Akhil B. Vaidya

Journal:

Molecular and Biochemical Parasitology

Année:

2011

Langue:

english

Fichier:

PDF, 497 KB

english, 2011

16

Stochastic versus stable transcriptional differences on Plasmodium falciparum DNA microarrays

Karthikeyan Ganesan, Lei Jiang, Pradipsinh K. Rathod

Journal:

International Journal for Parasitology

Année:

2002

Langue:

english

Fichier:

PDF, 324 KB

english, 2002

17

Gene organization of a Plasmodium falciparum serine hydroxymethyltransferase and its functional expression in Escherichia coli

Suad Alfadhli, Pradipsinh K Rathod

Journal:

Molecular and Biochemical Parasitology

Année:

2000

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2000

18

DNA microarrays for malaria

Pradipsinh K. Rathod, Karthikeyan Ganesan, Rhian E. Hayward, Zbynek Bozdech, Joseph L. DeRisi

Journal:

Trends in Parasitology

Année:

2002

Langue:

english

Fichier:

PDF, 120 KB

english, 2002

19

Bioisosteric Transformations and Permutations in the Triazolopyrimidine Scaffold To Identify the Minimum Pharmacophore Required for Inhibitory Activity against Plasmodium falciparum Dihydroorotate Dehydrogenase

Marwaha, Alka, White, John, El_Mazouni, Farah, Creason, Sharon A, Kokkonda, Sreekanth, Buckner, Frederick S., Charman, Susan A., Phillips, Margaret A., Rathod, Pradipsinh K.

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2012

20

Identification of mammalian aspartate-4-decarboxylase

Pradipsinh K. Rathod, Jack H. Fellman

Journal:

Archives of Biochemistry and Biophysics

Année:

1985

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1985

21

Regulation of mammalian aspartate-4-decarboxylase: Its possible role in oxaloacetate and energy metabolism

Pradipsinh K. Rathod, Jack H. Fellman

Journal:

Archives of Biochemistry and Biophysics

Année:

1985

Langue:

english

Fichier:

PDF, 480 KB

english, 1985

22

Plasmodium yoelii: Oral delivery of 5-fluoroorotate to treat malaria in mice

Pradipsinh K. Rathod, Zaida M. Gomez

Journal:

Experimental Parasitology

Année:

1991

Langue:

english

Fichier:

PDF, 209 KB

english, 1991

23

Malaria-attributed death rates in India

Ashwani Kumar, Virendra Kumar Dua, Pradipsinh K Rathod

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 50 KB

english, 2011

24

Response from Haldar, Lauer and Rathod

Kasturi Haldar, Sabine A. Lauer, Pradipsinh K. Rathod

Journal:

Trends in Microbiology

Année:

1997

Langue:

english

Fichier:

PDF, 200 KB

english, 1997

25

Estimating physical splenic filtration of Plasmodium falciparum-infected red blood cells in malaria patients

Thurston Herricks, Karl B. Seydel, Malcolm Molyneux, Terrie Taylor, Pradipsinh K. Rathod

Journal:

Cellular Microbiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2012

26

Antimalarial Agents Directed at Thymidylate Synthase

PRADIPSINH K. RATHOD

Journal:

Journal of Pharmacy and Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 501 KB

english, 1997

27

Kinetics and Ligand-Binding Preferences of Mycobacterium tuberculosis Thymidylate Synthases, ThyA and ThyX

Hunter, Joshua H., Gujjar, Ramesh, Pang, Cullen K. T., Rathod, Pradipsinh K., Abraham, Edathara

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 508 KB

english, 2008

28

A microfluidic system to study cytoadhesion of Plasmodium falciparum infected erythrocytes to primary brain microvascularendothelial cells

Herricks, Thurston, Seydel, Karl B., Turner, George, Molyneux, Malcolm, Heyderman, Robert, Taylor, Terrie, Rathod., Pradipsinh K.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 324 KB

english, 2011

29

Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors

Deng, Xiaoyi, Kokkonda, Sreekanth, El Mazouni, Farah, White, John, Burrows, Jeremy N., Kaminsky, Werner, Charman, Susan A., Matthews, David, Rathod, Pradipsinh K., Phillips, Margaret A.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2014

30

Variations in Frequencies of Drug Resistance in Plasmodium falciparum

Pradipsinh K. Rathod, Tara McErlean and Pei-Chieh Lee

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 777 KB

english, 1997

31

Analysis of Flavin Oxidation and Electron-Transfer Inhibition in Plasmodium falciparum Dihydroorotate Dehydrogenase †

Malmquist, Nicholas A., Gujjar, Ramesh, Rathod, Pradipsinh K., Phillips, Margaret A.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 274 KB

english, 2008

32

Atovaquone Tolerance in Plasmodium falciparum Parasites Selected for High-Level Resistance to a Dihydroorotate Dehydrogenase Inhibitor

Guler, Jennifer L., White, John, Phillips, Margaret A., Rathod, Pradipsinh K.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 418 KB

english, 2015

33

The X-ray structure of Plasmodium falciparum dihydroorotate dehydrogenase bound to a potent and selective N -phenylbenzamide inhibitor reveals novel binding-site interactions

Deng, Xiaoyi, Matthews, David, Rathod, Pradipsinh K., Phillips, Margaret A.

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2015

34

Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation

Gonzales, Joseph M., Patel, Jigar J., Ponmee, Napawan, Jiang, Lei, Tan, Asako, Maher, Steven P., Wuchty, Stefan, Rathod, Pradipsinh K., Ferdig, Michael T., Templeton, Thomas J.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 422 KB

english, 2008

35

A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates

Ganesan, Karthikeyan, Ponmee, Napawan, Jiang, Lei, Fowble, Joseph W., White, John, Kamchonwongpaisan, Sumalee, Yuthavong, Yongyuth, Wilairat, Prapon, Rathod, Pradipsinh K., Kim, Kami

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 509 KB

english, 2008

36

Asexual Populations of the Human Malaria Parasite, Plasmodium falciparum, Use a Two-Step Genomic Strategy to Acquire Accurate, Beneficial DNA Amplifications

Guler, Jennifer L., Freeman, Daniel L., Ahyong, Vida, Patrapuvich, Rapatbhorn, White, John, Gujjar, Ramesh, Phillips, Margaret A., DeRisi, Joseph, Rathod, Pradipsinh K., Su, Xin-zhuan

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2013

37

Structure of Plasmodium falciparum orotate phosphoribosyltransferase with autologous inhibitory protein–protein interactions

Kumar, Shiva, Krishnamoorthy, Kalyanaraman, Mudeppa, Devaraja G., Rathod, Pradipsinh K.

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2015

38

Microfluidic Modeling of Cell−Cell Interactions in Malaria Pathogenesis

Antia, Meher, Herricks, Thurston, Rathod, Pradipsinh K.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 434 KB

english, 2007

39

Topoisomerase II from Human Malaria Parasites

Mudeppa, Devaraja G., Kumar, Shiva, Kokkonda, Sreekanth, White, John, Rathod, Pradipsinh K.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2015

40

Anopheles subpictus carry human malaria parasites in an urban area of Western India and may facilitate perennial malaria transmission

Kumar, Ashwani, Hosmani, Rajeshwari, Jadhav, Shivaji, de Sousa, Trelita, Mohanty, Ajeet, Naik, Milind, Shettigar, Adarsh, Kale, Satyajit, Valecha, Neena, Chery, Laura, Rathod, Pradipsinh K.

Journal:

Malaria Journal

Année:

2016

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2016

41

Improved light microscopy counting method for accurately counting Plasmodium parasitemia and reticulocytemia

Lim, Caeul, Pereira, Ligia, Shardul, Pritish, Mascarenhas, Anjali, Maki, Jennifer, Rixon, Jordan, Shaw-Saliba, Kathryn, White, John, Silveira, Maria, Gomes, Edwin, Chery, Laura, Rathod, Pradipsinh K.,

Journal:

American Journal of Hematology

Année:

2016

Langue:

english

Fichier:

PDF, 716 KB

english, 2016

42

Reticulocyte Preference and Stage Development of Plasmodium vivax Isolates

Lim, Caeul, Pereira, Ligia, Saliba, Kathryn Shaw, Mascarenhas, Anjali, Maki, Jennifer N., Chery, Laura, Gomes, Edwin, Rathod, Pradipsinh K., Duraisingh, Manoj T.

Journal:

The Journal of Infectious Diseases

Année:

2016

Langue:

english

Fichier:

PDF, 773 KB

english, 2016

43

Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates

Shaw-Saliba, Kathryn, Clarke, David, Santos, Jorge M., Menezes, Maria José, Lim, Caeul, Mascarenhas, Anjali, Chery, Laura, Gomes, Edwin, March, Sandra, Bhatia, Sangeeta N., Rathod, Pradipsinh K., Ferr

Journal:

International Journal for Parasitology

Année:

2016

Langue:

english

Fichier:

PDF, 722 KB

english, 2016

44

NIH Public Access

Phillips, Margaret A, Gujjar, Ramesh, Malmquist, Nicholas A, White, John, El, Farah, Baldwin, Jeffrey, Rathod, Pradipsinh K

Année:

2009

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2009

45

Malaria in India: The Need for New Targets for Diagnosis And Detection of Plasmodium vivax

Patankar, Swati, Sharma, Shobhona, Rathod, Pradipsinh K., Duraisingh, Manoj

Journal:

PROTEOMICS - Clinical Applications

Année:

2017

Langue:

english

Fichier:

PDF, 794 KB

english, 2017

46

Enhanced ex vivo Plasmodium vivax intraerythrocytic enrichment and maturation for rapid and sensitive parasite growth assays

Rangel, Gabriel W., Clark, Martha A., Kanjee, Usheer, Lim, Caeul, Shaw-Saliba, Kathryn, Menezes, Maria José, Mascarenhas, Anjali, Chery, Laura, Gomes, Edwin, Rathod, Pradipsinh K., Ferreira, Marcelo U

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2018

47

Indispensable malaria genes

White, John, Rathod, Pradipsinh K.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 779 KB

english, 2018

48

Plasmodium Dihydroorotate Dehydrogenase: A Promising Target for Novel Anti-Malarial Chemotherapy

A. Phillips, Margaret, K. Rathod, Pradipsinh

Journal:

Infectious Disorders - Drug Targets(Formerly Current Drug Targets - Infectious Disorders)

Année:

2010

Langue:

english

Fichier:

PDF, 585 KB

english, 2010

49

A call to arms: Unifying the fight against resistance

Kaushansky, Alexis, Hedstrom, Lizbeth, Goldman, Aaron, Singh, Juswinder, Yang, Priscilla L., Rathod, Pradipsinh K., Cynamon, Michael, Wodarz, Dominik, Mahadevan, Daruka, Tomaras, Andrew, Navia, Manuel

Journal:

Science Signaling

Année:

2018

Langue:

english

Fichier:

PDF, 94 KB

english, 2018

50

Identification and mechanistic understanding of dihydroorotate dehydrogenase point mutations in Plasmodium falciparum that confer in vitro resistance to the clinical candidate DSM265

White, John, dhingra, satish, Deng, Xiaoyi, El Mazouni, Farah, Lee, Marcus, Afanador, Gustavo, Lawong, Aloysus, Tomchick, Diana R, Ng, Caroline L., Bath, Jade, Rathod, Pradipsinh K, Fidock, David A, P

Journal:

ACS Infectious Diseases

Année:

2018

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2018